I'm drawing shapes into a picture box using API functions. I tried defining the scale  (Set ScaleMode to inches and set the scale of the picture box and the origins using the 'Scale' method)  BUT changing the scale seems to have absolutely no effect on the size of the APIs as they're drawn out - it always comes out the same size and does not seem to be according to the set scale... Ideas?  

Well, API's use pixels for drawing, so, if you are passing values in twips, convert those values to pixels, and then send this values to API's. To convert twips to pixels, you can use form's ScaleX and ScaleY methods, for horisontal/vertical conversion, respectively.

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